2,065 research outputs found

    The concept of gender in government documents on health and nutrition in Mexico

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    Objectives: This article has two central objectives; to review the inclusion of the term gender\u27 in seven government documents on health and nutrition in Mexico, and to interpret the rationale underlying their use.\u2

    Problematic, absent and stigmatizing diagnoses in current mental disorders classifications: Results from the WHO-WPA and WHO-IUPsyS Global Surveys

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    This study examined English- and Spanish-speaking psychologists' and psychiatrists' opinions regarding problematic, absent and stigmatizing diagnoses in current mental disorders classifications (ICD-10 and DSM-IV), and their perceived need for a national classification of mental disorders. Answers to open-ended questions included in WHO-WPA and WHO-IUPsyS surveys were examined using an inductive content-analysis method. A total of 3,222 participants from 35 countries were included. The most problematic diagnostic group was personality disorders, especially among psychiatrists, because of poor validity and lack of specificity. Complex posttraumatic stress disorder was the most frequent diagnosis suggested for inclusion, mainly by psychologists, to better account for the distinct processes and consequences of complex trauma. Schizophrenia was the diagnosis most frequently identified as stigmatizing, particularly by psychiatrists, due to lack of public understanding or knowledge about the diagnosis. Of the 14.4% of participants who perceived a need for a national classification system, two-thirds were from Africa or Latin America. The rationales provided were that mental disorders classifications should consider cultural and socio-historical diversity in the expression of psychopathology, differences in the perception of what is and is not pathological in different nations, and the existence of culture-bound syndromes. Implications for ICD-11 development and dissemination are discussed. © 2014 Asociación Española de Psicología Conductual

    An overview of the health effects of bisphenol a from a one health perspective

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    Bisphenol A (BPA) is a chemical compound, considered as an “emerging pollutant”, that appears ubiquitously, contaminating the environment and food. It is an endocrine disruptor, found in a multitude of consumer products, as it is a constituent of polycarbonate used in the manufacture of plastics and epoxy resins. Many studies have evaluated the effects of BPA, using a wide range of doses and animal models. In this work, we carried out a review of relevant research related to the effects of BPA on health, through studies performed at different doses, in different animal models, and in human monitoring studies. Numerous effects of BPA on health have been described; in different animal species, it has been reported that it interferes with fertility in both females and males and causes alterations in their offspring, as well as being associated with an increase in hormone-dependent pathologies. Similarly, exposure to BPA has been related to other diseases of great relevance in public health such as obesity, hypertension, diabetes, or neurodevelopmental disorders. Its ubiquity and nonmonotonic behavior, triggering effects at exposure levels considered “safe”, make it especially relevant when both animal and human populations are constantly and inadvertently exposed to this compound. Its effects at low exposure levels make it essential to establish safe exposure levels, and research into the effects of BPA must continue and be focused from a “One Health” perspective to take into account all the factors that could intervene in the development of a disease in any exposed organism

    Analysis of Indirect Biomarkers of Effect after Exposure to Low Doses of Bisphenol A in a Study of Successive Generations of Mice

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    Bisphenol A (BPA) is considered as being an emerging pollutant, to which both animal and human populations are continuously and inadvertently exposed. The identification of indirect biomarkers of effect could be a key factor in determining early adverse outcomes from exposure to low doses of BPA. Thus, this study on mice aims to evaluate and identify indirect biomarkers of effect through the analysis of their blood biochemistry, and of certain reproduction parameters after exposure to different BPA concentrations (0.5, 2, 4, 50, and 100 µg/kg BW/day) in drinking water over generations. Our results showed that there were no modifications in the reproductive parameters evaluated, like estrous cycle duration, litter size, or the percentage of the young alive at reaching the weaning stage, at the exposure levels evaluated. However, there were modifications in the biochemical parameters, e.g., alterations in the glucose levels, that increased significantly (p < 0.05) in the breeders at the higher exposure doses (50 and 100 µg/kg BW/day in F1; 50 µg/kg BW/day in F2 and 100 µg/kg BW/day in F3), that would suggest that the BPA could induce hyperglycemia and its complications in adult animals, probably due to some damage in the pancreas cells; albumin, that increased in the breeders exposed to the highest dose in F1 and F3, inferring possible hepatic alterations. Further, total proteins showed a diminution in their values in F1 and F2, except the group exposed to 100 µg/kg BW/day, whereas in F3 the values of this parameter increased with respect to the control group, this aspect likely being related to a possible hepatic and renal alteration. Based on these results, glucose, albumin, and total proteins could initially be considered as early indicators of indirect effect after prolonged exposure to low BPA doses over generations

    Diseño de una red de sensores inalámbricos para el despliegue óptimo de los nodos sensores en un cultivo de Cacao

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    In this study, factorial experiments were conducted in two different scenarios to design a Wireless Sensor Network for monitoring a cocoa crop in a rural area in Colombia. Node sensors measured temperature, relative humidity, soil moisture, Ultra-Violet light, and visible light intensity. The factors considered in the experiments were distance between node sensors, height from the ground, and type of antenna; in turn, Received Signal Strength Indicator and data transfer time were the outputs. The wireless sensor network was deployed in the crop, covering approximately 3 % of the area and using 7 different nodes in a cluster tree topology. First, an open field scenario with line of sight was used to determine the appropriate height of the node sensors. Second, a scenario in the actual cocoa crop was utilized to find the appropriate distance between modules and type of antenna. We found, based on our calculations and experimental data, that a height of 1.25 m was required to avoid the Fresnel zone and improve the RSSI of the network. Furthermore, we determined that a distance below 35 m was needed to guarantee signal reception and avoid long data transfer times. The wire antenna exhibited a better performance. Finally, the proposed methodology and monitoring system can be used for agronomic applications in rural areas in Colombia to increase crop yield.En este trabajo se realizaron experimentos factoriales en dos escenarios diferentes, para diseñar una red de sensores inalámbricos, que permita monitorear un cultivo de cacao en una zona rural de Colombia. Los nodos sensores miden la temperatura, la humedad relativa, la humedad del suelo, la luz ultravioleta y la intensidad de la luz visible. Los factores considerados en los experimentos fueron la distancia entre los nodos sensores, la altura con respecto al suelo y el tipo de antena; el indicador de intensidad de señal recibida y el tiempo de transferencia de datos fueron las salidas. La red de sensores inalámbricos se implementó en el cultivo, cubriendo aproximadamente el 3 % del área, utilizando 7 nodos diferentes en una topología de cluster-tree. En primer lugar, se utilizó un escenario de campo abierto con línea de vista para determinar la altura adecuada de los sensores de nodo. Luego, se utilizó un escenario en el cultivo de cacao real para encontrar la distancia adecuada entre los módulos y el tipo de antena. Se obtuvo, por cálculos y datos experimentales, que se requería una altura de 1.25 m para evitar la zona de Fresnel y mejorar el RSSI de la red. Además, se determinó que se necesitaba una distancia inferior a 35 m para garantizar la recepción de la señal y evitar largos tiempos de transferencia de datos. Adicionalmente, la antena tipo Wire exhibió un mayor rendimiento y la metodología propuesta y el sistema de monitoreo se pueden usar para aplicaciones agronómicas en áreas rurales de Colombia, con el fin de aumentar el rendimiento de los cultivos

    Evaluation of the Toxicity of Bisphenol A in Reproduction and Its Effect on Fertility and Embryonic Development in the Zebrafish (Danio rerio)

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    Bisphenol A (BPA) is a chemical substance commonly used in the manufacture of plastic products. Its inhalation or ingestion from particles in suspension, water, and/or polluted foods can trigger toxic effects related to endocrine disruption, resulting in hormonal, reproduction, and immunological alterations in humans and animals. The zebrafish (Danio rerio) is an ideal experimental model frequently used in toxicity studies. In order to assess the toxic effects of BPA on reproduction and embryonic development in one generation after parental exposure to it, a total of 80 zebrafish, males and females, divided into four groups in duplicate (n = 20) were exposed to BPA concentrations of 500, 50, and 5 µg L−1, along with a control group. The fish were kept in reproduction aquariums for 21 days. The embryos obtained in the crosses were incubated in a BPA-free medium and observed for signs of embryotoxicity. A histopathological study (under optical and electron microscopes) was performed of adult fish gonads. The embryos of reproducers exposed to BPA were those most frequently presenting signs of embryotoxicity, such as mortality and cardiac and musculoskeletal malformations. In the histopathological studies of adult individuals, alterations were found in ovocyte maturation and in spermatazoid formation in the groups exposed to the chemical. Those alterations were directly related to BPA action, affecting fertility in both sexes, as well as the viability of their offspring, proportionally to the BPA levels to which they were exposed, so that our results provide more information by associating toxic effects on the offspring and on the next generation

    Cardiovascular Magnetic Resonance Imaging Evidence of Edema in Chronic Chagasic Cardiomyopathy

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    The persistence of inflammatory processes in the myocardium in varying degrees of chronic Chagas heart disease has been poorly investigated. We hypothesized that edema could occur in patients with chronic chagasic cardiomyopathy and corresponds to the persistence of inflammatory processes in the myocardium. Eighty-two Chagas disease (CD) seropositive patients (64.6% females; age = 58.9 ± 9.9) without ischemic heart disease or conditions that cause myocardial fibrosis and dilation were considered. Late gadolinium enhancement (LGE) and T2-weighted magnetic resonance imaging of edema were obtained and represented using a 17-segment model. Patients were divided into three clinical groups according to the left ventricular (LV) ejection fraction (EF) as G1 (EF > 60%; ), G2 (35% > EF  35% (). Deteriorations of the LV and RV systolic functions were positively correlated (; ) without evidence of LGE in the RV. Edema can be found in patients with chagasic cardiomyopathy in the chronic stage. In later stages of cardiac dilation with low LVEF, the LGE pattern involves subendocardium and mid locations. Deteriorations of RV and LV are positively correlated without evidence of fibrosis in the RV

    Development and implementation of a collaborative blog as a co-assessment instrument in Veterinary Medicine Degree

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    La evaluación educativa pretende comprometer al alumnado en su proceso de enseñanza-aprendizaje mediante el uso de estrategias e instrumentos de coevaluación y autoevaluación. En este sentido, las tecnologías de la información y de la comunicación (TIC) promueven un clima de enseñanza más dinámico a través del aprendizaje activo, siendo los blogs colaborativos una herramienta muy útil de evaluación del alumnado. El objetivo de este proyecto ha sido evaluar la implementación de un blog como instrumento educativo para promover la autorregulación por medio de actividades de coevaluación y/o autoevaluación en el ámbito universitario. Se diseñó un blog de divulgación científica como recurso docente para la asignatura optativa de “el Animal de Laboratorio”, perteneciente al Grado de Veterinaria. Se evaluó mediante cuestionarios tanto la situación inicial del alumnado, como los logros finales respecto al objetivo planteado, siguiendo una metodología descriptiva. Según los resultados obtenidos, es innegable decir que el uso del blog ha sido una práctica innovadora, siendo en muchos casos la primera experiencia con TIC para el alumnado. Respecto a su implementación, los resultados han sido satisfactorios para la mejora motivacional, el aprendizaje y la dinamización metodológica. Todo ello, pone de manifiesto las múltiples ventajas que ofrecen los blogs como herramienta de coevaluación.The educational evaluation aims to engage students in their teaching-learning process through the use of strategies and instruments of co-assessment and self-assessment In this sense, information and communication technologies (ICT) promote a more dynamic teaching environment through active learning, and collaborative blogs appear as a very useful tool for student assessment. The aim of this project has been to evaluate the implementation of a blog as an educational instrument to promote self-regulation through co-evaluation and / or self-evaluation activities at the university. To this end, a scientific dissemination blog was designed as a teaching resource for the optional subject “the Laboratory Animal”, belonging to the Veterinary Science Degree syllabus. The starting point of the learning process of the students was evaluated by questionnaires, as well as the final achievements related to the proposed objective, following a descriptive methodology. According to the obtained results, it is undeniable that the development of the blog has been an innovative practice, being in many cases the first experience with ICT for students. Regarding its implementation, results suggest that students‟ motivation has improved, and the learning procedure and methodologies applied have been dynamized. All this shows the many advantages that blogs offer as a co-assessment tool
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